2.9 - Advanced Night Repair Serum

1. Technical Overview

The Nightly Follicular Activation Serum is the growth-phase component of the ABORA Ecosystem. It is engineered to directly target the dermal papilla and hair follicle stem cells to reinforce anagen (growth) signalling, provide structural anchoring support, and combat follicular miniaturization. Its role is to actively promote the hair growth cycle on a scalp environment pre-conditioned by the Daily Scalp Optimiser, completing the topical intervention strategy.

ACTIVE INGREDIENT SYSTEM

• Redensyl at 3.00% w/w
  *Complex: Dihydroquercetin-glucoside, EGCG2, Zinc chloride. Standardized, patented compound.*

• Procapil at 3.00% w/w
  Complex: Oleanolic Acid, Apigenin, Biotinyl-GHK. Standardized, patented compound.

• Capixyl at 5.00% w/w
  *Complex: Acetyl Tetrapeptide-3, Red Clover Extract. Standardized, patented compound.*

• Anagain at 4.00% w/w
  Pisum Sativum (Pea) Sprout Extract. Standardized, patented compound.

• Baicapil at 3.00% w/w
  Complex: Scutellaria Baicalensis Root, Glycine Soja (Soybean) Germ, Triticum Vulgare (Wheat) Germ. Standardized, patented compound.

2. Specification: Targeted Pathways & Active Components

Targeted Pathway: Stem Cell Exhaustion & Quiescence

• Primary Failure Mode: Dormant follicle stem cells failing to activate new growth cycles.

• Key Actives: Redensyl, Baicapil.

• Certified Mechanism: Direct targeting and activation of stem cells in the hair follicle bulge region; promotion of the transition from telogen (resting) to anagen (growth) phase.

Targeted Pathway: Shortened Anagen (Growth) Phase & Poor Signalling

• Primary Failure Mode: Inadequate growth duration and weak proliferative signals to the hair matrix.

• Key Actives: Anagain, Procapil.

• Certified Mechanism: Extension of the anagen phase duration; modulation of key growth factors (e.g., VEGF, FGF-7) and inhibition of apoptosis in dermal papilla cells.

Targeted Pathway: Follicle Anchoring & Structural Weakness

• Primary Failure Mode: Poor attachment of the follicle to the dermis, leading to miniaturization.

• Key Actives: Procapil, Capixyl.

• Certified Mechanism: Reinforcement of the dermal-epidermal junction and follicular basement membrane; reduction of perifollicular fibrosis to improve nutrient delivery and structural integrity.

3. Position in the Full ABORA Ecosystem

This serum is specifically formulated to address Pathways #4 (Reduced Blood Flow), #5 (Stem Cell Exhaustion), and aspects of #3 (Scalp Fibrosis) of the 12 identified causes of hair thinning. It is designed for nightly use to actively stimulate and support the growth phase. It is engineered to be applied after the Daily Scalp Optimiser, ideally at night, relying on the stabilized environment it creates.