2.8 - Copper Peptide Serum

1. Technical Overview

The Copper Peptide Regeneration Serum is the post-procedural specialist component of the ABORA Ecosystem. It is engineered to harness the signalling power of high-purity copper peptides to directly support tissue repair, collagen remodelling, and follicular recovery following microneedling. Its role is to transform the mechanical stimulation of microneedling into a precise biochemical signal for regeneration, ensuring the scalp environment heals optimally and is primed for growth.

USE: Alongside Microneedling Hn20 Hydra Stamp

ACTIVE INGREDIENT SYSTEM

• Copper Tripeptide-1 (GHK-Cu) at 1.00% w/w
  *High-purity copper peptide (99.87% HPLC). Elemental copper content: 11.85%. Identity confirmed by ESI-MS.*

• Alanine/Histidine/Lysine Polypeptide Copper HCl (AHK-Cu) at 0.50% w/w
  *High-purity copper peptide complex (98.58% HPLC). AHK peptide content: ≥71.06%. Elemental copper content: 11.63%. Identity confirmed by ESI-MS.*

FORMULATION BASE:

• Aqua (Deionized Water)

• Propanediol (humectant and solvent system)

STABILITY & CONTROL SYSTEMS:

• Phenoxyethanol and Ethylhexylglycerin (preservation system)

• Disodium EDTA (chelator)

• Citric Acid and Sodium Hydroxide (for pH adjustment to 6.2–6.8)

2. Specification: Targeted Pathways & Active Components

This serum is formulated to address the regenerative needs created by controlled mechanical stimulation, focusing on repair and signalling fidelity.

• Targeted Pathway: Tissue Remodelling & Fibrosis

  • Primary Goal: Promote healthy extracellular matrix (ECM) remodelling and mitigate improper healing that can lead to perifollicular fibrosis.

  • Key Actives: Copper Tripeptide-1 (GHK-Cu), AHK-Cu.

  • Certified Mechanism: Upregulation of collagen types I, III, and IV synthesis; regulation of MMPs (matrix metalloproteinases) for balanced ECM turnover; direct anti-fibrotic signalling.

• Targeted Pathway: Angiogenic & Repair Signalling

  • Primary Goal: Enhance nutrient and oxygen delivery to support follicle repair and activation post-procedure.

  • Key Actives: Copper Tripeptide-1 (GHK-Cu).

  • Certified Mechanism: Stimulation of angiogenic factors (e.g., VEGF); activation of wound-healing and tissue remodelling pathways (TGF-β3).

• Targeted Pathway: Cellular Stress Response & Protection

  • Primary Goal: Protect follicles and dermal cells from oxidative stress associated with the healing process.

  • Key Actives: Copper Tripeptide-1 (GHK-Cu).

  • Certified Mechanism: Potent antioxidant activity; upregulation of endogenous antioxidant enzymes (SOD); protection against UV-induced damage.

3. Position in the Full ABORA Ecosystem

This serum is the protocol-driven regeneration layer. It is specifically engineered to exploit the transient "window of opportunity" following microneedling, directly addressing the repair aspects of Pathway #3 (Scalp Fibrosis) and providing critical support for Pathway #5 (Stem Cell Exhaustion) through enhanced environmental signalling. Its use is restricted to post-microneedling application to ensure maximal peptide efficacy and to avoid disrupting the distinct, daily functions of the Scalp Optimiser and Nightly Activation serums. It is a mandatory step for translating mechanical stimulation into long-term biological gains within the ABORA protocol.